Welcome to the laboratory of Saurabh Sinha at the University of Illinois, Urbana-Champaign.
Our research focuses on computational approaches to problems in molecular biology. In particular, we are interested in exploring gene regulation, mostly in metazoan genomes. We approach the subject through an integrated analysis of DNA sequence, gene expression, and epigenetic data. We also strive to understand how sequences involved in gene regulation have evolved, and how such evolutionary dynamics may inform the discovery of novel regulatory sequences. Broadly speaking, our work falls in the areas of regulatory and comparative genomics.
Principal Investigator: Saurabh Sinha.
POST-DOC POSITION AVAILABLE: See here.
FEATURED NEW RESEARCH: Framework to model the expression of a gene from its entire intergenic locus
Md. Abul Hassan Samee, Saurabh Sinha (2014). Quantitative modeling of a gene's expression from its intergenic sequence. PLoS computational biology 10 (3), e1003467. [Full Text]